| Date | Size | Title | Author |
| January 3, 2010 | 21 x 21 | ANTIQUE FINISH | Jeremy Newton |
| January 10, 2010 | 21 x 21 | CROSS WORDS | Mel Rosen |
| January 17, 2010 | 21 x 21 | SUBTLETIES | Cathy Allis |
| January 24, 2010 | 23 x 23 | ABRIDGED EDITION | David Kwong and Kevan Choset |
| January 31, 2010 | 21 x 21 | KEEP AN EYE ON IT! | Tony Orbach and Andrea Carla Michaels |
| February 7, 2010 | 23 x 23 | THE FOOTBALL FAN | Patrick Berry |
| February 14, 2010 | 21 x 21 | THAT'S AMORE | Matt Ginsberg and Pete Muller |
| February 21, 2010 | 21 x 21 | WORDS FROM THE WHITE HOUSE | Eric Berlin |
| February 28, 2010 | 21 x 21 | EASE-E DOES IT | Yaakov Bendavid |
| March 7, 2010 | 21 x 21 | COME TO ORDER | Tony Orbach and Patrick Blindauer |
| March 14, 2010 | 23 x 23 | BOOK BINDING | Caleb Madison |
| March 21, 2010 | 21 x 21 | THEM'S THE BREAKS | Adam Fromm |
| March 28, 2010 | 21 x 21 | WHAT MAKES IT ITCH? | Ed Sessa |
| April 4, 2010 | 21 x 21 | AFTER WORD | Bob Klahn |
| April 11, 2010 | 21 x 21 | TEE TIME | Patrick Berry |
| April 18, 2010 | 21 x 21 | WHATS-ITS | Randolph Ross |
| April 25, 2010 | 21 x 21 | MONUMENTAL ACHIEVEMENT | Elizabeth C. Gorski |
| May 2, 2010 | 21 x 21 | FIX-A-TION | Kelsey Blakley |
| May 9, 2010 | 21 x 21 | MS. CONCEPTIONS | Elizabeth C. Gorski |
| May 16, 2010 | 21 x 21 | DOUBLE CROSSERS | Matt Ginsberg |
| May 23, 2010 | 21 x 21 | FLIP-FLOPS | Yaakov Bendavid |
| May 30, 2010 | 21 x 21 | FULL CIRCLE | Eric Berlin |
| June 6, 2010 | 21 x 21 | TYPECASTING | Daniel A. Finan |
| June 13, 2010 | 21 x 21 | FLAG DAY | Francis Heaney |
| June 20, 2010 | 21 x 21 | PUBLISHING TRADE | Todd Gross and Ashish Vengsarkar |
| June 27, 2010 | 21 x 21 | TO THINE OWN SELF BE TRUE | Michael J. Doran |
| July 4, 2010 | 21 x 21 | MAKING ENDS MEET | Patrick Blindauer and Tony Orbach |
| July 11, 2010 | 21 x 21 | AS ELMER FUDD WOULD SAY ... | Ed Sessa |
| July 18, 2010 | 21 x 21 | CRITICAL PERIODS | Robert W. Harris |
| July 25, 2010 | 21 x 21 | UP STARTS | Alan Arbesfeld |
| August 1, 2010 | 21 x 21 | PLAY BARGAINING | Brendan Emmett Quigley |
| August 8, 2010 | 21 x 21 | 3 X 8 | Pam Klawitter |
| August 15, 2010 | 21 x 21 | IS THERE AN ECHO IN HERE? | Daniel C. Bryant |
| August 22, 2010 | 21 x 21 | FILM NO-R | Patrick Berry |
| August 29, 2010 | 21 x 21 | GOING FOR A RUN | Derek Bowman |
| September 5, 2010 | 21 x 21 | TURNING BACK | Will Nediger |
| September 12, 2010 | 21 x 21 | IT'S GOING TO COST YOU | Paula Gamache |
| September 19, 2010 | 21 x 21 | MUSICAL PLAY | Kevin G. Der |
| September 26, 2010 | 21 x 21 | LOCATION, LOCATION, LOCATION | Pamela Amick Klawitter |
| October 3, 2010 | 21 x 21 | CAN I CHANGE PLACES? | Daniel A. Finan |
| October 10, 2010 | 21 x 21 | DRIVERS' TRANSLATIONS | Patrick Merrell |
| October 17, 2010 | 21 x 21 | FIGURE OF SPEECH | Patrick Blindauer |
| October 24, 2010 | 21 x 21 | RISKY BUSINESS | Brendan Emmett Quigley |
| October 31, 2010 | 21 x 21 | FANGS FOR THE MEMORY | Elizabeth C. Gorski |
| November 7, 2010 | 21 x 21 | LEADING ARTICLES | Will Nediger |
| November 14, 2010 | 21 x 21 | DOUBLEHEADERS | Patrick Berry |
| November 21, 2010 | 21 x 21 | HAVING ASPIRATIONS | Clive Probert |
| November 28, 2010 | 23 x 23 | A SHINING MOMENT | Jeremy Newton |
| December 5, 2010 | 21 x 21 | ON A ROLL | Ben Pall |
| December 12, 2010 | 21 x 21 | THE WISH | Karen Young Bonin |
| December 19, 2010 | 23 x 23 | HOPE FOR CLEAR SKIES | Kevin G. Der |
| December 26, 2010 | 21 x 21 | HEY, MISTER! | Darin McDaniel |